Breaking News, Collaborations & Alliances

iTeos Therapeutics, GSK Enter Monoclonal Antibody Alliance

GSK now has a leading portfolio of antibodies targeting the CD226 axis, a key target for next-gen immuno-oncology therapies

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By: Kristin Brooks

Managing Editor, Contract Pharma

iTeos Therapeutics and GlaxoSmithKline plc entered an agreement to co-develop and co-commercialize EOS-448, an anti-TIGIT monoclonal antibody currently in phase I development as a potential treatment for cancer. TIGIT, part of the CD226 checkpoint axis, has demonstrated potential as a promising target for the next generation of immuno-oncology therapies based on preclinical data and a phase II randomized clinical trial. With this collaboration has access to antibodies that synergistically target...

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